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Liquid biopsy is a transformative diagnostic approach that detects biological markers, such as circulating tumor DNA and extracellular vesicles, within a simple blood sample. This method provides a non-invasive alternative to traditional tissue biopsies, enabling the identification and tracking of genetic mutations without requiring invasive surgical procedures or tissue extraction.

The process relies on the extraction and sequencing of DNA fragments that have been shed into the bloodstream by diseased cells. Because these fragments carry the unique genetic signatures of the original tissue, they can be analyzed to identify specific mutations, resistance patterns, or clonal evolutions. This allows for a "real-time" look at a patient’s condition that would be difficult to capture with a static, localized physical biopsy.

One of the primary benefits of this technology is its ability to facilitate longitudinal monitoring. Clinicians can perform serial blood draws over time to observe how a disease changes or responds to…

The treatment landscape for rare neurological diseases has been transformed by the advent of personalized medicine. For many years, treatment was limited to physical therapy and palliative care. However, with the discovery of the genetic drivers behind conditions like Spinal Muscular Atrophy (SMA), scientists have developed therapies that fundamentally alter the course of the disease. For instance, medications that modify the splicing of genes allow the body to produce essential proteins that were previously absent, preventing the rapid loss of motor neurons and improving mobility in affected children.

In addition to genetic therapies, the repurposing of existing compounds and the development of novel small molecules are playing a vital role. In rare autoimmune neurological disorders, such as certain types of encephalitis or Neuromyelitis Optica, targeted monoclonal antibodies are being used to suppress the specific parts of the immune system that are attacking the nervous system. These biological therapies offer a…

I wanted to let everyone know that our next Coach Appreciation Draw will be February 28, 2026. This initiative allows coaches one entry for every SSBC session they have delivered up until the end of the month. The draw will be held in each region and winners will receive a prize. If you have any questions, drop them below  :)

Welcome to our group Small Steps Group! A space for us to connect and share with each other. Start by posting your thoughts, sharing media, or creating a poll.

I found the mock session pretty hard and awkward at first. It was challenging to keep the flow of conversation going while trying to use motivational, open-ended questions the way the program encourages. I didn’t feel very natural at first.

What really helped me was practicing in my own way. I used ChatGPT to run through mock scenarios that were tailored to the SSBC style. I could role-play different situations, ask for corrections, and then try again until it started to feel more comfortable.

Getting ready for your mock session? We have made a video breaking down everything you will need to know to be successful. Click the link: https://www.youtube.com/watch?v=9p5JQAi368Q & Good Luck!

My client has been trying to use the HW app (on android). all looks fine and is working as expected, until we get a 'suggestion / tips pop up window' that locks up the app. We deleted and reinstalled the app, same issue. Any techies have any advice?

Hello folks, I am was unable to collect a HbA1c sample from one of my clients during their first session. What do I do if I can't extract enough blood for a sample? After the normal process was unsuccessful I had the client walk around, swing their arms, run their hands under warm water and still couldn't get even half a sample size. They have multiple heath things going on right now and may be on medication that effects blood flow to the extremities. They have really cold hands.

Should I try taking a sample after the exercise portion? I know that's not best practice but I am not sure where to go from here.

Take 5 minutes today to reflect on your last coaching session. What did you do well? What could you improve? Share your insights and let’s learn together!